OLOS

A Unique Multi‑Centre Resource for Advancing Critical Care Research of Sepsis patients

We are proud to introduce the Sepsis Anonymized Data Set, a groundbreaking clinical data resource designed to accelerate innovation in intensive care medicine, sepsis research, and data driven healthcare solutions.

This high‑quality data set adhere to international standards notably in terms of ontologies (e.g. ATC, LOINC, SNOMED CT) and FAIR data. Following the rules is brings together comprehensive clinical information from 90,000 ICU patients, collected across five leading medical centers. Through rigorous anonymization and harmonization procedures, it provides researchers with an unprecedented opportunity to explore the complexity of critical illness at scale—while maintaining the highest standards of data privacy and ethical integrity.

Compared to similar initiatives like MIMIC or eICU, our dataset will also contain rich molecular data on pathogens e.g., bacterial whole genome sequencing and MALDI-TOF MS spectra. This notably enables investigating further aspects like the impact of antimicrobial resistance and virulence in ICU patients. In addition, domain knowledge also integrates to the dataset, thanks to the prospectively collected contextual information. For the established data concepts focusing e.g. on laboratory, microbiology, treatment data, regular quality controls ensure a low amount of missing data, which is an issue in many other databases.

The data set comprises of following data packages and corresponding data
Demographics
  • Administrative Case
  • Administrative Sex
  • Age
  • Body Height Measurement
  • Consent
  • Death
  • Healthcare Encounter
  • Home Address

Medical history
  • Access Device Presence
  • Allergy
  • Implant Presence
  • Transplant Presence

Laboratory
Physiological data
  • Blood Pressure Measurement
  • Body Mass Index
  • Body Temperature Measurement
  • Body Weight Measurement
  • Cardiac Index
  • Cardiac Output Measurement
  • Fluid Balance
  • Fluid Input Output
  • Heart Rate Measurement
  • Oxygen Saturation Measurement
  • Respiratory Rate Measurement
  • Fraction Of Inspired Oxygen Measurement
  • Mean Inspiratory Airway Pressure Measurement
  • Minute Ventilation Measurement
  • Peak Inspiratory Pressure Measurement
  • Positive End Expiratory Pressure Measurement
Microbiology
  • Antimicrobial Susceptibility Lab Test Event
  • Microbiology Biomolecule Presence Lab Test Event
  • Microbiology Microscopy Lab Test Event
  • Microorganism Identification Lab Test Event
  • Sample Processing
  • Sequencing Analysis
  • Sequencing Assay
  • Matrix Assisted Laser Desorption Ionization Time Of Flight Mass Spectrometry Assay

Diagnosis
  • Assessment Event
  • Problem Condition
  • Billed Diagnosis Procedure

 

Physiological data
  • Blood Pressure Measurement
  • Body Mass Index
  • Body Temperature Measurement
  • Body Weight Measurement
  • Cardiac Index
  • Cardiac Output Measurement
  • Fluid Balance
  • Fluid Input Output
  • Heart Rate Measurement
  • Oxygen Saturation Measurement
  • Respiratory Rate Measurement
  • Fraction Of Inspired Oxygen Measurement
  • Mean Inspiratory Airway Pressure Measurement
  • Minute Ventilation Measurement
  • Peak Inspiratory Pressure Measurement
  • Positive End Expiratory Pressure Measurement

Dear researchers, contact us for details if you are interested to obtain access to our data set or would need further information or support.

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